RETN

Across TCGA pan-cancer cohorts, RETN mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RETN data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RETN mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RETN expression acts as an unfavorable survival marker, although some lineages such as CCRCC and OV show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where RETN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.197	0.787	.006	33	view →
PDAC	DFS	Tertile	All	0.732	0.920	.013	15	view →
CCRCC	DFS	Tertile	IV	1.000	0.189	.024	12	view →
OV	DFS	Median	All	0.876	0.479	.012	8	view →
GBM	OS	Tertile	All	0.820	0.685	.047	5	view →
HNSC	DFS	Median	III,IV	0.712	0.891	.040	3	view →
UCEC	DFS	Median	All	1.000	0.936	.021	2	view →
LSCC	DFS	Tertile	All	0.742	0.353	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RETN–LUAD (OS)

Open the LUAD breakdown →