RESP18

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RESP18 RNA expression is significantly associated with the protein abundance of many other proteins, with 4,420 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RESP18-associated proteins across cancer lineages are CEP170B_S360, DYNC1LI1_S207, and WNK2. Each is linked with RESP18 in more than 1 cancer types. Because this analysis shows association rather than direction, both RESP18-to-partner and partner-to-RESP18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RESP18 versus CEP170B_S360 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RESP18→partner) and Y-score (partner→RESP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCEP170B_S360 →+0.525+0.231<.001<.00132
LSCCDYNC1LI1_S207 →+0.269+0.070<.001.00532
GBMWNK2 →+0.551+0.190<.001<.00132
PDACASRGL1 →+0.421+0.020.002.00532
PDACBAX →-0.215-0.021<.001.00432
GBMCHGB_S130 →+1.363+0.347<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,420 associations by consensus.

RESP18 vs CEP170B_S360 — GBM

Per-sample scatter of RESP18 vs CEP170B_S360 in GBM (Pearson r = 0.34).

Explore this scatter interactively →

Exploration