RESP18

Across TCGA cell cohorts, RESP18 RNA expression is significantly associated with the mutation status of many other genes, with 160 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RESP18-associated genes across cancer lineages are NOS1, EXPH5, and ATRNL1. Each is linked with RESP18 in more than 1 cancer types. Because this analysis shows association rather than direction, both RESP18-to-partner and partner-to-RESP18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOS1 grouped by RESP18-low versus RESP18-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RESP18→partner) and Y-score (partner→RESP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NOS1 →	+2.483	+0.111	.003	.001	3	2
LUNG_SCLC	EXPH5 →	+2.635	+0.131	.007	<.001	3	2
LUNG_NSCLC_LUAD	ATRNL1 →	+2.362	+0.013	.008	<.001	3	2
LUNG_NSCLC_LUAD	TRPC4 →	+2.555	+0.013	.006	<.001	3	2
LUNG_NSCLC_LUAD	PTPN13 →	+2.555	+0.014	.006	<.001	3	2
LUNG_NSCLC_LUAD	ZNF366 →	+3.362	+0.021	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

NOS1 by RESP18 expression — LUNG_SCLC

Explore this box plot interactively →