RERG-AS1

Across TCGA pan-cancer cohorts, RERG-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RERG-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RERG-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RERG-AS1 is over-expressed in tumor, although a few such as KIRP and UCEC show the opposite, repressed pattern.

KIRP, UCEC, and HNSC are the cancer types where RERG-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RERG-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−2.304	<.001	10	view →
UCEC	All	All	−0.637	<.001	6	view →
HNSC	All	All	−0.128	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RERG-AS1–KIRP

Open the KIRP breakdown →