RER1

Across TCGA patient cohorts, RER1 mutation is significantly associated with the RNA expression of many other genes, with 995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RER1-associated genes across cancer lineages are RN7SL237P, TBC1D3I, and RN7SKP25. Each is linked with RER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RER1-to-partner and partner-to-RER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL237P grouped by RER1-low versus RER1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RER1→partner) and Y-score (partner→RER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL237P →	+0.244	+5.418	<.001	.005	3	2
SKCM	TBC1D3I →	+0.022	+4.838	<.001	.002	3	1
SKCM	RN7SKP25 →	+0.118	+4.680	<.001	.007	3	1
SKCM	RNU6-514P →	+0.430	+5.508	<.001	<.001	3	1
SKCM	RNU6-1311P →	+0.476	+4.513	<.001	.009	3	1
SKCM	MIR150 →	+0.442	+4.470	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 995 associations by consensus.

RN7SL237P by RER1 expression — CESC

Explore this box plot interactively →