RER1

Across TCGA cell cohorts, RER1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,160 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RER1-associated GO terms across cancer lineages are Protein retention in ER lumen, Phospholipid biosynthetic process, and Protein insertion into ER membrane. Each is linked with RER1 in more than 14 cancer types. Because this analysis shows association rather than direction, both RER1-to-partner and partner-to-RER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein retention in ER lumen grouped by RER1-low versus RER1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RER1→partner) and Y-score (partner→RER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein retention in ER lumen →	+0.185	+0.959	<.001	<.001	3	15
OVARY	Phospholipid biosynthetic process →	+0.029	+0.537	<.001	<.001	2	13
SKIN	Protein insertion into ER membrane →	+0.110	+0.678	<.001	<.001	3	11
LARGE_INTESTINE	Endoplasmic reticulum to cytosol transport →	+0.118	+0.725	<.001	<.001	3	11
LARGE_INTESTINE	Retrograde protein transport, ER to cytosol →	+0.118	+0.725	<.001	<.001	3	11
SOFT_TISSUE	Regulation of intracellular transport →	+0.034	+0.516	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,160 associations by consensus.

Protein retention in ER lumen by RER1 expression — SOFT_TISSUE

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