REEP1

Across TCGA patient cohorts, REEP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,000 significant associations in total. GBM shows the largest number of these associations.

The most reproducible REEP1-associated genes across cancer lineages are LIPE, PCSK6, and SNPH. Each is linked with REEP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both REEP1-to-partner and partner-to-REEP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REEP1 versus LIPE in COAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP1→partner) and Y-score (partner→REEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LIPE →	+0.883	+1.151	.001	.005	3	4
UCEC	PCSK6 →	+1.262	+0.782	<.001	<.001	3	3
BRCA	SNPH →	+0.740	+0.649	.003	.002	3	3
GBM	ASPA →	+0.607	+0.399	.008	.006	3	3
GBM	GNRHR →	+0.364	+0.413	.005	.004	3	3
GBM	PDE1A →	+1.076	+0.817	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,000 associations by consensus.

REEP1 vs LIPE — COAD

Explore this scatter interactively →