REEP1

Across TCGA cell cohorts, REEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,679 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible REEP1-associated GO terms across cancer lineages are Positive regulation of DNA repair, Epigenetic regulation of gene expression, and Farnesyl diphosphate metabolic process. Each is linked with REEP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both REEP1-to-partner and partner-to-REEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by REEP1-low versus REEP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP1→partner) and Y-score (partner→REEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of DNA repair →	+0.053	+0.989	.001	<.001	3	13
LIVER	Epigenetic regulation of gene expression →	+0.058	+1.315	.002	.004	3	13
OVARY	Farnesyl diphosphate metabolic process →	+0.155	+0.914	<.001	.001	3	12
LIVER	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.069	+1.423	<.001	.003	3	12
LIVER	mRNA splicing, via spliceosome →	+0.069	+1.423	<.001	.003	3	12
OESOPHAGUS	ATP biosynthetic process →	+0.124	+1.409	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,679 associations by consensus.

Positive regulation of DNA repair by REEP1 expression — OVARY

Explore this box plot interactively →