RECQL

Across TCGA patient cohorts, RECQL RNA expression is significantly associated with the protein abundance of many other proteins, with 15,323 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RECQL-associated proteins across cancer lineages are P3H1, PDHA1, and PDHB. Each is linked with RECQL in more than 5 cancer types. Because this analysis shows association rather than direction, both RECQL-to-partner and partner-to-RECQL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RECQL versus P3H1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RECQL→partner) and Y-score (partner→RECQL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	P3H1 →	+0.582	+0.632	<.001	<.001	3	5
BRCA	PDHA1 →	-0.394	-0.573	<.001	<.001	3	5
BRCA	PDHB →	-0.359	-0.627	<.001	<.001	3	5
GBM	P3H3 →	+0.756	+0.383	<.001	<.001	3	5
UCEC	SLC25A4 →	-0.711	-0.659	<.001	<.001	3	5
COAD	ITGA5 →	+0.508	+0.493	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,323 associations by consensus.

RECQL vs P3H1 — BRCA

Explore this scatter interactively →