RECQL

Across TCGA patient cohorts, RECQL protein abundance is significantly associated with the RNA expression of many other genes, with 10,143 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RECQL-associated genes across cancer lineages are GOLT1B, CCN4, and PARP11. Each is linked with RECQL in more than 6 cancer types. Because this analysis shows association rather than direction, both RECQL-to-partner and partner-to-RECQL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RECQL versus GOLT1B in LUAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RECQL→partner) and Y-score (partner→RECQL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GOLT1B →	+0.726	+0.342	<.001	<.001	3	7
COAD	CCN4 →	+1.287	+0.367	<.001	<.001	3	5
UCEC	PARP11 →	+0.611	+0.262	<.001	<.001	3	5
OV	CHD4 →	+0.576	+0.445	<.001	<.001	3	5
OV	FGFR1OP2 →	+0.579	+0.323	<.001	<.001	3	5
COAD	GFPT2 →	+0.798	+0.194	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,143 associations by consensus.

RECQL vs GOLT1B — LUAD

Explore this scatter interactively →