RECQL

Across TCGA patient cohorts, RECQL mutation is significantly associated with the RNA expression of many other genes, with 1,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RECQL-associated genes across cancer lineages are SC4MOP, VN2R1P, and C1QTNF9-AS1. Each is linked with RECQL in more than 2 cancer types. Because this analysis shows association rather than direction, both RECQL-to-partner and partner-to-RECQL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SC4MOP grouped by RECQL-low versus RECQL-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RECQL→partner) and Y-score (partner→RECQL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SC4MOP →	+0.136	+3.963	<.001	.003	3	3
BRCA	VN2R1P →	+0.051	+5.211	.001	.001	3	2
CESC	C1QTNF9-AS1 →	+0.118	+5.103	.005	.008	3	2
STAD	RNU6-234P →	+0.325	+5.217	<.001	<.001	3	2
STAD	MIR495 →	+0.352	+3.562	<.001	.007	3	2
STAD	LINC02779 →	+0.329	+4.031	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,799 associations by consensus.

SC4MOP by RECQL expression — STAD

Explore this box plot interactively →