RECK

Across TCGA patient cohorts, RECK protein abundance is significantly associated with the RNA expression of many other genes, with 14,274 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RECK-associated genes across cancer lineages are CNRIP1, DPT, and SRPX. Each is linked with RECK in more than 8 cancer types. Because this analysis shows association rather than direction, both RECK-to-partner and partner-to-RECK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RECK versus CNRIP1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RECK→partner) and Y-score (partner→RECK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	+0.976	+0.527	<.001	<.001	3	9
COAD	DPT →	+1.731	+0.860	<.001	<.001	3	9
BRCA	SRPX →	+1.293	+0.559	<.001	<.001	3	8
BRCA	CRISPLD2 →	+1.269	+0.658	<.001	<.001	3	8
OV	CXCL12 →	+1.821	+0.583	<.001	<.001	3	8
CCRCC	C7 →	+2.012	+0.307	.003	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,274 associations by consensus.

RECK vs CNRIP1 — BRCA

Explore this scatter interactively →