Across TCGA patient cohorts, REC114 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,401 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible REC114-associated proteins across cancer lineages are VPS13D_S2671, PHF2_S655, and SEC63_T537. Each is linked with REC114 in more than 5 cancer types. Because this analysis shows association rather than direction, both REC114-to-partner and partner-to-REC114 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (REC114→partner) and Y-score (partner→REC114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VPS13D_S2671 →	-0.878	-0.625	.001	<.001	3	6
HNSC	PHF2_S655 →	+0.729	+0.889	<.001	<.001	3	5
PDAC	SEC63_T537 →	-0.990	-0.672	<.001	<.001	3	5
PDAC	SF3B1_T426 →	+0.495	+0.519	<.001	<.001	3	5
LSCC	SF3B1_S129 →	+0.482	+0.395	<.001	.002	3	5
HNSC	NDEL1_S198 →	-0.805	-1.043	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,401 associations by consensus.

Exploration

REC114 survival (RNA) · tumor vs normal (RNA) · all REC114 data types