RDM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RDM1 protein abundance is significantly associated with the RNA expression of many other genes, with 653 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RDM1-associated genes across cancer lineages are HMOX1, NFKBIA, and SIRPB1. Each is linked with RDM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDM1-to-partner and partner-to-RDM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDM1 versus HMOX1 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDM1→partner) and Y-score (partner→RDM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHMOX1 →+1.504+1.393.003.00131
GBMNFKBIA →+1.380+1.891.009.00331
GBMSIRPB1 →+0.613+1.524.003.00131
GBMLAMA1 →-1.216-1.197.008.00831
GBMPOLA1 →-0.845-1.647.009.00231
GBMSMARCA1 →-0.605-1.588.003.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 653 associations by consensus.

RDM1 vs HMOX1 — GBM

Per-sample scatter of RDM1 vs HMOX1 in GBM (Pearson r = 0.58).

Explore this scatter interactively →

Exploration