Across TCGA pan-cancer cohorts, RDM1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of RDM1’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RDM1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RDM1 is over-expressed in tumor.
BLCA, KIRC, and KIRP are the cancer types where RDM1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RDM1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.