RDH12

Across TCGA patient cohorts, RDH12 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,124 significant associations in total. THCA shows the largest number of these associations.

The most reproducible RDH12-associated GO terms across cancer lineages are Aerobic respiration, Primary alcohol metabolic process, and Thioester metabolic process. Each is linked with RDH12 in more than 13 cancer types. Because this analysis shows association rather than direction, both RDH12-to-partner and partner-to-RDH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by RDH12-low versus RDH12-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH12→partner) and Y-score (partner→RDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Aerobic respiration →	+0.040	+0.406	<.001	<.001	3	14
STAD	Primary alcohol metabolic process →	+0.034	+0.649	<.001	<.001	3	14
STAD	Thioester metabolic process →	+0.030	+0.312	<.001	.002	3	14
UVM	Proton motive force-driven ATP synthesis →	+0.056	+0.874	<.001	.005	3	13
LGG	Synaptic vesicle lumen acidification →	+0.036	+0.246	<.001	<.001	3	12
STAD	Endosomal lumen acidification →	+0.039	+0.483	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,124 associations by consensus.

Aerobic respiration by RDH12 expression — LAML

Explore this box plot interactively →