RDH12

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RDH12 protein abundance is significantly associated with the RNA expression of many other genes, with 8,838 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RDH12-associated genes across cancer lineages are SLC25A40, RAE1, and FSD1. Each is linked with RDH12 in more than 2 cancer types. Because this analysis shows association rather than direction, both RDH12-to-partner and partner-to-RDH12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDH12 versus SLC25A40 in OV, with a Pearson correlation of -0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH12→partner) and Y-score (partner→RDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSLC25A40 →-1.013-2.163.002.00533
PDACRAE1 →-0.455-0.555.002.00132
HNSCFSD1 →-0.646-0.698<.001<.00132
HNSCPASK →-0.733-0.977<.001<.00132
HNSCNEK2 →-0.995-0.723<.001<.00132
PDACCENPF →-0.962-0.565.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,838 associations by consensus.

RDH12 vs SLC25A40 — OV

Per-sample scatter of RDH12 vs SLC25A40 in OV (Pearson r = -0.79).

Explore this scatter interactively →

Exploration