RDH12

Across TCGA patient cohorts, RDH12 mutation is significantly associated with the RNA expression of many other genes, with 2,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RDH12-associated genes across cancer lineages are RNU6-1126P, RN7SKP192, and GPHB5. Each is linked with RDH12 in more than 2 cancer types. Because this analysis shows association rather than direction, both RDH12-to-partner and partner-to-RDH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1126P grouped by RDH12-low versus RDH12-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH12→partner) and Y-score (partner→RDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1126P →	+0.348	+6.444	<.001	.001	3	3
BLCA	RN7SKP192 →	+0.259	+4.266	<.001	.003	3	2
LIHC	GPHB5 →	+0.080	+5.108	.002	.008	3	2
LIHC	RNU1-28P →	+0.277	+5.878	<.001	.002	3	2
UCEC	PACS2 →	+0.422	+3.191	.002	.009	3	2
UCEC	DYNC1H1 →	+0.500	+3.467	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,048 associations by consensus.

RNU6-1126P by RDH12 expression — LUAD

Explore this box plot interactively →