RDH12

Across TCGA cell cohorts, RDH12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,716 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RDH12-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of proteasomal protein catabolic process, and Positive regulation of TORC1 signaling. Each is linked with RDH12 in more than 6 cancer types. Because this analysis shows association rather than direction, both RDH12-to-partner and partner-to-RDH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by RDH12-low versus RDH12-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH12→partner) and Y-score (partner→RDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.075	+0.201	.004	.002	3	6
BREAST	Regulation of proteasomal protein catabolic process →	+0.040	+0.289	.004	.001	2	7
BREAST	Positive regulation of TORC1 signaling →	+0.059	+0.300	<.001	.003	3	5
BREAST	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.041	-0.265	.007	.003	3	5
LUNG_NSCLC_LUSC	Vesicle targeting, to, from or within Golgi →	+0.092	+0.500	.002	.007	2	6
LIVER	Fatty acid catabolic process →	+0.094	+0.291	.009	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by RDH12 expression — OVARY

Explore this box plot interactively →