RDH11

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RDH11 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RDH11 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RDH11 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RDH11 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where RDH11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSTertileAll0.9460.753.00313view →
LUADDFSQuartileII,III,IV0.2170.762.0168view →
UCECDFSQuartileAll0.7981.000.0274view →
PDACOSTertileIV0.4720.934.0243view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RDH11–CCRCC (OS)

Kaplan–Meier survival curve for RDH11 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration