RDH11

Across TCGA patient cohorts, RDH11 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RDH11-associated genes across cancer lineages are aDC, Epithelial cells, and Basophils. Each is linked with RDH11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH11-to-partner and partner-to-RDH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by RDH11-low versus RDH11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH11→partner) and Y-score (partner→RDH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.102	+2.839	.006	.034	3	1
UCEC	Epithelial cells →	-0.117	-2.989	.001	.035	3	1
UCEC	Basophils →	+0.183	+2.321	.031	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

aDC by RDH11 expression — UCEC

Explore this box plot interactively →