RDH11

Across TCGA cell cohorts, RDH11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RDH11-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Each is linked with RDH11 in more than 9 cancer types. Because this analysis shows association rather than direction, both RDH11-to-partner and partner-to-RDH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by RDH11-low versus RDH11-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH11→partner) and Y-score (partner→RDH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.192	+0.705	<.001	<.001	3	10
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.192	+0.705	<.001	<.001	3	10
BONE	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.115	+0.857	<.001	<.001	3	9
PANCREAS	Response to sterol depletion →	+0.114	+0.865	<.001	<.001	3	9
KIDNEY	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.062	+1.222	.001	.004	3	8
PANCREAS	Negative regulation of amyloid-beta clearance →	+0.136	+0.737	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,139 associations by consensus.

Protein catabolic process at synapse by RDH11 expression — BLOOD_Lymphoma

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