RDH10-AS1

Across TCGA pan-cancer cohorts, RDH10-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RDH10-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RDH10-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RDH10-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UVM, and COAD are the cancer types where RDH10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.485	0.253	<.001	133	view →
UVM	DFS	Tertile	III,IV	0.219	0.813	<.001	92	view →
COAD	DFS	Median	All	0.392	0.633	<.001	73	view →
KIRP	DFS	Quartile	All	0.479	0.837	<.001	64	view →
THCA	OS	Tertile	All	0.948	0.995	.002	50	view →
LGG	DFS	Median	All	0.667	0.810	<.001	48	view →
ACC	OS	Quartile	All	0.380	0.760	<.001	43	view →
READ	DFS	Tertile	All	0.720	0.932	.001	30	view →
KIRC	DFS	Quartile	III,IV	0.219	0.558	.007	29	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LUSC	OS	Tertile	II,III,IV	0.818	0.641	.003	16	view →
DLBC	DFS	Tertile	All	0.425	0.932	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RDH10-AS1–HNSC (OS)

Open the HNSC breakdown →