RCVRN

Across TCGA patient cohorts, RCVRN mutation is significantly associated with the RNA expression of many other genes, with 1,717 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCVRN-associated genes across cancer lineages are TAF9, NUDT18, and TUBGCP5. Each is linked with RCVRN in more than 1 cancer types. Because this analysis shows association rather than direction, both RCVRN-to-partner and partner-to-RCVRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by RCVRN-low versus RCVRN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCVRN→partner) and Y-score (partner→RCVRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.476	+1.807	<.001	.004	3	2
UCEC	NUDT18 →	+0.518	+1.923	.002	.009	3	2
UCEC	TUBGCP5 →	+0.376	+2.954	.002	<.001	3	2
COAD	SENP3-EIF4A1 →	+0.217	+3.273	<.001	.008	3	2
UCEC	COX15 →	+0.453	+1.807	<.001	.004	3	2
UCEC	SLC25A4 →	+0.601	+3.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,717 associations by consensus.

TAF9 by RCVRN expression — UCEC

Explore this box plot interactively →