RCVRN

Across TCGA cell cohorts, RCVRN mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RCVRN-associated genes across cancer lineages are MAS1, GJD2, and PM20D1. Each is linked with RCVRN in more than 1 cancer types. Because this analysis shows association rather than direction, both RCVRN-to-partner and partner-to-RCVRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAS1 grouped by RCVRN-low versus RCVRN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCVRN→partner) and Y-score (partner→RCVRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAS1 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	PM20D1 →	+0.328	+3.643	<.001	.005	3	1
LARGE_INTESTINE	PDILT →	+0.005	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR4F4 →	+0.013	+4.009	.001	<.001	3	1
LARGE_INTESTINE	CHRM2 →	+0.019	+3.426	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MAS1 by RCVRN expression — LARGE_INTESTINE

Explore this box plot interactively →