RCL1

Across TCGA cell cohorts, RCL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,347 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RCL1-associated GO terms across cancer lineages are Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with RCL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both RCL1-to-partner and partner-to-RCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by RCL1-low versus RCL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCL1→partner) and Y-score (partner→RCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.127	+1.075	<.001	<.001	3	19
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.139	+1.191	.001	<.001	3	18
OESOPHAGUS	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.139	+1.009	.008	<.001	3	18
URINARY_TRACT	Maturation of 5.8S rRNA →	+0.089	+0.665	.001	.009	3	17
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.161	+1.196	<.001	<.001	3	15
OVARY	rRNA processing →	+0.120	+1.045	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,347 associations by consensus.

Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by RCL1 expression — UPPER_AERODIGESTIVE_TRACT

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