RCL1

Across TCGA pan-cancer cohorts, RCL1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RCL1 data layer compared with 6 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RCL1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RCL1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

KIRC, BRCA, and LIHC are the cancer types where RCL1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.723	0.514	<.001	58	view →
BRCA	DFS	Median	All	0.927	0.875	<.001	53	view →
LIHC	OS	Median	All	0.699	0.445	<.001	49	view →
OV	OS	Median	All	0.882	0.802	.002	30	view →
GBM	DFS	Quartile	All	0.411	0.134	<.001	26	view →
UCEC	DFS	Tertile	All	0.786	0.891	.002	22	view →
LGG	OS	Quartile	All	0.831	0.697	.006	20	view →
PAAD	DFS	Median	All	0.409	0.552	.009	14	view →
SKCM	DFS	Quartile	IV	0.635	0.048	<.001	14	view →
UCS	OS	Quartile	All	0.594	0.837	.004	12	view →
KIRP	DFS	Median	All	0.913	0.605	.004	10	view →
LUAD	DFS	Median	All	0.736	0.617	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RCL1–KIRC (DFS)

Open the KIRC breakdown →