RCL1

Across TCGA cell cohorts, RCL1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible RCL1-associated genes across cancer lineages are LGI1, ASB10, and OR6B1. Each is linked with RCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCL1-to-partner and partner-to-RCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGI1 grouped by RCL1-low versus RCL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCL1→partner) and Y-score (partner→RCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	1
STOMACH	ASB10 →	+0.016	+5.285	<.001	.003	3	1
STOMACH	OR6B1 →	+0.020	+5.285	<.001	.003	3	1
BLOOD_Leukemia	CYP1A2 →	+0.040	+4.125	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

LGI1 by RCL1 expression — BLOOD_Leukemia

Explore this box plot interactively →