RCHY1

Across TCGA pan-cancer cohorts, RCHY1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RCHY1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RCHY1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RCHY1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where RCHY1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.645	0.971	<.001	26	view →
UCEC	DFS	Median	III,IV	1.000	0.424	.003	24	view →
LUAD	DFS	Median	II,III,IV	0.640	0.265	.008	11	view →
HNSC	OS	Median	IV	0.842	0.624	.014	8	view →
PDAC	DFS	Median	III,IV	0.876	0.421	.013	6	view →
GBM	OS	Median	All	0.654	0.862	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RCHY1–CCRCC (DFS)

Open the CCRCC breakdown →