RCC2

Across TCGA patient cohorts, RCC2 mutation is significantly associated with the RNA expression of many other genes, with 1,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCC2-associated genes across cancer lineages are MIR6782, RN7SKP60, and VN1R93P. Each is linked with RCC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCC2-to-partner and partner-to-RCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6782 grouped by RCC2-low versus RCC2-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC2→partner) and Y-score (partner→RCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	MIR6782 →	+0.554	+5.316	<.001	.006	3	2
SKCM	RN7SKP60 →	+0.119	+4.469	<.001	.006	3	2
LIHC	VN1R93P →	+0.060	+5.149	.002	.003	3	2
LIHC	RNU6-973P →	+0.242	+4.647	<.001	.007	3	2
LIHC	LINC01047 →	+0.052	+6.343	<.001	<.001	3	2
LIHC	RN7SL861P →	+0.154	+5.547	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,899 associations by consensus.

MIR6782 by RCC2 expression — KIRC

Explore this box plot interactively →