RCAN2

Across TCGA patient cohorts, RCAN2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,513 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RCAN2-associated genes across cancer lineages are SMAD7, MAPK3, and TUBB4A. Each is linked with RCAN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCAN2-to-partner and partner-to-RCAN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RCAN2 versus SMAD7 in CCRCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCAN2→partner) and Y-score (partner→RCAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SMAD7 →	+0.521	+0.942	.009	.007	3	2
CCRCC	MAPK3 →	+0.505	+1.568	.006	.003	3	2
GBM	TUBB4A →	+1.208	+0.634	.004	<.001	3	2
LSCC	PPIF →	-1.068	-0.675	.004	.006	3	2
CCRCC	SLC17A2 →	+1.654	+1.875	<.001	<.001	3	2
CCRCC	AMD1 →	+0.909	+1.619	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,513 associations by consensus.

RCAN2 vs SMAD7 — CCRCC

Explore this scatter interactively →