RC3H2

Across TCGA patient cohorts, RC3H2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,370 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RC3H2-associated genes across cancer lineages are RUBCNL, NRM, and GGH. Each is linked with RC3H2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RC3H2-to-partner and partner-to-RC3H2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RC3H2 versus RUBCNL in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RC3H2→partner) and Y-score (partner→RC3H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RUBCNL →	-0.733	-0.300	<.001	.001	3	2
LSCC	NRM →	+0.434	+0.138	.002	.005	3	2
UCEC	GGH →	+0.653	+0.124	.003	.006	3	2
UCEC	ZNF474 →	-1.154	-0.155	.002	.005	3	2
UCEC	TEKT1 →	-1.492	-0.155	.001	.001	3	2
BRCA	TCP11L1 →	+0.518	+0.312	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,370 associations by consensus.

RC3H2 vs RUBCNL — HNSC

Explore this scatter interactively →