RBSN

Across TCGA pan-cancer cohorts, RBSN mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RBSN data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RBSN mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RBSN expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where RBSN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.993	0.714	<.001	71	view →
LUAD	OS	Quartile	All	0.930	0.697	.008	12	view →
UCEC	OS	Quartile	II,III,IV	0.519	1.000	.033	8	view →
PDAC	DFS	Tertile	IV	0.224	0.777	.024	6	view →
LSCC	DFS	Quartile	III,IV	0.548	1.000	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RBSN–CCRCC (OS)

Open the CCRCC breakdown →