RBSN

Across TCGA patient cohorts, RBSN mutation is significantly associated with the RNA expression of many other genes, with 2,578 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBSN-associated genes across cancer lineages are LINC02297, MIR8053, and CCDC43. Each is linked with RBSN in more than 2 cancer types. Because this analysis shows association rather than direction, both RBSN-to-partner and partner-to-RBSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02297 grouped by RBSN-low versus RBSN-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBSN→partner) and Y-score (partner→RBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02297 →	+0.044	+4.306	<.001	.001	3	3
LUAD	MIR8053 →	+0.421	+5.343	.001	.006	3	3
UCEC	CCDC43 →	+0.511	+2.032	<.001	<.001	3	3
UCEC	RPL23AP82 →	+0.352	+2.524	<.001	<.001	3	3
UCEC	PSMC3IP →	+0.609	+1.765	<.001	<.001	3	3
UCEC	SMC2 →	+0.653	+3.169	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,578 associations by consensus.

LINC02297 by RBSN expression — CESC

Explore this box plot interactively →