RBPMS-AS1

Across TCGA pan-cancer cohorts, RBPMS-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RBPMS-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher RBPMS-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RBPMS-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUAD show a favorable association.

LGG, BLCA, and LUAD are the cancer types where RBPMS-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.737	0.876	<.001	47	view →
BLCA	DFS	Median	All	0.704	0.547	<.001	46	view →
LUAD	OS	Quartile	All	0.847	0.715	.002	41	view →
COAD	DFS	Tertile	IV	0.696	0.170	<.001	37	view →
SARC	OS	Median	All	0.889	0.781	<.001	27	view →
ACC	OS	Quartile	IV	0.906	0.221	.006	24	view →
PAAD	DFS	Quartile	All	0.386	0.694	.004	22	view →
LIHC	OS	Tertile	III,IV	0.737	0.308	.018	13	view →
UCEC	DFS	Quartile	All	0.741	0.629	.011	12	view →
GBM	DFS	Median	All	0.188	0.366	.007	9	view →
KIRC	DFS	Median	All	0.694	0.558	.015	8	view →
BRCA	OS	Median	III,IV	0.877	0.774	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RBPMS-AS1–LGG (OS)

Open the LGG breakdown →