RBPMS-AS1

Across TCGA pan-cancer cohorts, RBPMS-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RBPMS-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RBPMS-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RBPMS-AS1 is over-expressed in tumor, although a few such as THCA and HNSC show the opposite, repressed pattern.

THCA, KIRP, and HNSC are the cancer types where RBPMS-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBPMS-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−1.620	<.001	11	view →
KIRP	All	II,III,IV	+1.324	<.001	11	view →
HNSC	All	II,III,IV	−0.720	<.001	11	view →
COAD	Male	IV	+1.017	<.001	10	view →
LUAD	Male	III,IV	−2.380	<.001	9	view →
LUSC	Male	All	−2.495	<.001	8	view →
KIRC	All	All	+0.716	<.001	8	view →
BRCA	All	All	−1.360	<.001	6	view →
KICH	Male	All	−0.940	<.001	6	view →
LIHC	All	All	+0.429	.001	4	view →
BLCA	Male	III,IV	−0.784	.010	3	view →
CHOL	Male	All	+0.885	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RBPMS-AS1–THCA

Open the THCA breakdown →