RBPJL

Across TCGA cell cohorts, RBPJL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBPJL-associated GO terms across cancer lineages are Regulation of cytoplasmic pattern recognition receptor signaling pathway, Cilium movement, and Actin filament depolymerization. Each is linked with RBPJL in more than 4 cancer types. Because this analysis shows association rather than direction, both RBPJL-to-partner and partner-to-RBPJL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic pattern recognition receptor signaling pathway grouped by RBPJL-low versus RBPJL-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBPJL→partner) and Y-score (partner→RBPJL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.050	+0.013	<.001	.004	3	5
OVARY	Cilium movement →	-0.037	-0.026	.005	<.001	3	5
URINARY_TRACT	Actin filament depolymerization →	+0.169	+0.042	<.001	.004	3	5
LARGE_INTESTINE	Regulation of pattern recognition receptor signaling pathway →	+0.050	+0.015	<.001	.006	2	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to nucleus →	+0.065	+0.015	.006	.007	2	5
OVARY	Positive regulation of protein import into nucleus →	+0.068	+0.027	.003	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,145 associations by consensus.

Regulation of cytoplasmic pattern recognition receptor signaling pathway by RBPJL expression — LARGE_INTESTINE

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