RBP3

Across TCGA patient cohorts, RBP3 mutation is significantly associated with the RNA expression of many other genes, with 7,032 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBP3-associated genes across cancer lineages are MCMBP, REXO5, and AURKA. Each is linked with RBP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RBP3-to-partner and partner-to-RBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MCMBP grouped by RBP3-low versus RBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBP3→partner) and Y-score (partner→RBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCMBP →	+0.439	+1.375	<.001	<.001	3	5
UCEC	REXO5 →	+0.271	+1.538	.004	.002	3	5
LUAD	AURKA →	+0.731	+2.712	.001	.003	3	4
LUAD	BIRC5 →	+0.903	+2.459	.001	<.001	3	4
LUAD	CDC45 →	+1.147	+3.000	<.001	<.001	3	4
UCEC	CWF19L1 →	+0.269	+1.343	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,032 associations by consensus.

MCMBP by RBP3 expression — UCEC

Explore this box plot interactively →