RBP3

Across TCGA pan-cancer cohorts, RBP3 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RBP3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RBP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBP3 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

BLCA, KIRP, and THCA are the cancer types where RBP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.124	.001	6	view →
KIRP	All	All	−0.061	<.001	6	view →
THCA	All	All	−0.012	<.001	6	view →
LUSC	All	All	+0.099	<.001	5	view →
KICH	All	All	−0.065	.001	5	view →
KIRC	Male	All	−0.048	<.001	5	view →
LUAD	All	IV	+0.075	.004	2	view →
STAD	Female	All	−0.041	.025	2	view →
BRCA	All	All	−0.038	.023	2	view →
UCEC	All	IV	+0.035	.019	2	view →
PRAD	All	All	−0.018	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RBP3–BLCA

Open the BLCA breakdown →