RBP3

Across TCGA patient cohorts, RBP3 mutation is significantly associated with the total protein of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBP3-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-B1, and ASNS. Each is linked with RBP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both RBP3-to-partner and partner-to-RBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by RBP3-low versus RBP3-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBP3→partner) and Y-score (partner→RBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Caspase-7-cleavedD198 →	+0.862	+2.816	.001	.036	1	6
UCEC	Cyclin-B1 →	+0.548	+2.169	<.001	.002	3	4
UCEC	ASNS →	+0.290	+1.064	.003	.043	3	4
LUAD	PDK1_pS241 →	-0.149	-1.485	.019	.028	3	3
UCEC	IGFBP2 →	-0.507	-1.584	.004	.008	3	3
UCEC	GAPDH →	+0.536	+2.070	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

Caspase-7-cleavedD198 by RBP3 expression — LUSC

Explore this box plot interactively →