RBP3

Across TCGA cell cohorts, RBP3 mutation is significantly associated with the mutation status of many other genes, with 2,830 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBP3-associated genes across cancer lineages are COL6A6, ZNF407, and KIAA1109. Each is linked with RBP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RBP3-to-partner and partner-to-RBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL6A6 grouped by RBP3-low versus RBP3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBP3→partner) and Y-score (partner→RBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	COL6A6 →	+2.232	+2.232	<.001	<.001	1	5
SKIN	ZNF407 →	+2.647	+2.089	.002	.002	1	5
LUNG_NSCLC_LUAD	KIAA1109 →	+1.750	+2.159	.009	.009	1	5
BLOOD_Leukemia	KCNH2 →	+2.913	+2.913	.003	.003	1	5
LUNG_NSCLC_LUAD	ABCC11 →	+2.750	+2.459	.008	.008	1	5
LUNG_NSCLC_LUAD	PCNX2 →	+3.165	+2.670	.004	.004	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,830 associations by consensus.

COL6A6 by RBP3 expression — SKIN

Explore this box plot interactively →