RBP1

Across TCGA pan-cancer cohorts, RBP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RBP1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, OV, and LSCC are the cancer types where RBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.813	0.416	.005	13	view →
OV	DFS	Tertile	All	0.515	0.923	.009	8	view →
LSCC	OS	Median	III,IV	0.901	0.495	.022	3	view →
HNSC	DFS	Median	III,IV	0.849	0.360	.045	2	view →
LUAD	DFS	Tertile	II,III,IV	0.669	0.289	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RBP1–CCRCC (DFS)

Open the CCRCC breakdown →