RBMY2FP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBMY2FP mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RBMY2FP-associated genes across cancer lineages are TRAJ46, SRIP2, and ZBTB45P2. Each is linked with RBMY2FP in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMY2FP-to-partner and partner-to-RBMY2FP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ46 grouped by RBMY2FP-low versus RBMY2FP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMY2FP→partner) and Y-score (partner→RBMY2FP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTRAJ46 →+0.535+5.594<.001.00431
SKCMSRIP2 →+0.254+5.680<.001.00331
SKCMZBTB45P2 →+0.030+5.292.002.00631
SKCMTIMM9P1 →+0.322+4.979<.001.00931
SKCMOR7E53P →+0.051+5.292.001.00631
SKCMPSMB7P1 →+0.093+6.469<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TRAJ46 by RBMY2FP expression — SKCM

Box plot of TRAJ46 in RBMY2FP-low vs RBMY2FP-high samples in SKCM.

Explore this box plot interactively →

Exploration