RBMY1E

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RBMY1E RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RBMY1E data layer compared with 1 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RBMY1E RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RBMY1E expression acts as an unfavorable survival marker.

BRCA, LUAD, and GBM are the cancer types where RBMY1E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.3370.925<.001126view →
LUADOSTertileIII,IV0.0570.680<.00199view →
GBMOSTertileAll0.0300.416<.00136view →
THCAOSTertileAll0.1880.942<.00136view →
LUSCOSTertileIII,IV0.1450.690.00136view →
PCPGOSTertileAll0.0210.962<.00136view →
LGGOSTertileAll0.3930.812.03318view →
LIHCDFSTertileAll0.4440.580.02612view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RBMY1E–BRCA (OS)

Kaplan–Meier survival curve for RBMY1E RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration