RBMY1E

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RBMY1E RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RBMY1E’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RBMY1E RNA is repressed in tumor relative to normal tissue. In most cancer types RBMY1E is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC and LIHC are the cancer types where RBMY1E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBMY1E RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll−0.010.0026view →
LIHCMaleAll+0.052.0072view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RBMY1E–KIRC

Tumor-vs-normal expression box plot for RBMY1E RNA in KIRC.

Open the KIRC breakdown →

Exploration