RBMY1E

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RBMY1E Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RBMY1E data layer compared with 8 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RBMY1E Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBMY1E expression acts as an unfavorable survival marker.

GBM are the cancer types where RBMY1E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSMedianAll0.0660.257.0196view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

RBMY1E–GBM (DFS)

Kaplan–Meier survival curve for RBMY1E mutant vs wild-type samples in GBM.

Open the GBM breakdown →

Exploration