Across TCGA pan-cancer cohorts, RBMY1E Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RBMY1E data layer compared with 8 for mass-spec protein.
The strongest signal is observed in glioblastoma multiforme (GBM), where higher RBMY1E Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBMY1E expression acts as an unfavorable survival marker.
GBM are the cancer types where RBMY1E Mutation most reproducibly stratifies survival.