RBMX

Across TCGA cell cohorts, RBMX mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBMX-associated genes across cancer lineages are TACR3, EBF2, and KCNG4. Each is linked with RBMX in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMX-to-partner and partner-to-RBMX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TACR3 grouped by RBMX-low versus RBMX-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMX→partner) and Y-score (partner→RBMX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TACR3 →	+0.024	+4.060	<.001	.003	3	1
BLOOD_Leukemia	EBF2 →	+0.310	+3.999	<.001	.005	3	1
LARGE_INTESTINE	KCNG4 →	+0.006	+5.415	<.001	.004	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.018	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	SPATA48 →	+0.006	+5.662	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

TACR3 by RBMX expression — BLOOD_Leukemia

Explore this box plot interactively →