RBMS3-AS3

Across TCGA pan-cancer cohorts, RBMS3-AS3 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RBMS3-AS3 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RBMS3-AS3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RBMS3-AS3 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

UCS, BLCA, and KIRP are the cancer types where RBMS3-AS3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.623	0.134	.001	78	view →
BLCA	OS	Tertile	All	0.516	0.688	<.001	60	view →
KIRP	DFS	Quartile	II,III,IV	0.178	0.692	.001	45	view →
LGG	OS	Median	All	0.498	0.377	<.001	41	view →
ESCA	DFS	Tertile	II,III,IV	0.828	0.123	.016	34	view →
UCEC	DFS	Tertile	All	0.576	0.816	<.001	34	view →
MESO	OS	Median	II,III,IV	0.480	0.629	.013	29	view →
LIHC	DFS	Median	All	0.410	0.214	.001	27	view →
KIRC	OS	Quartile	All	0.770	0.575	<.001	22	view →
PCPG	DFS	Tertile	All	0.980	0.816	.004	20	view →
HNSC	DFS	Median	All	0.434	0.654	.002	20	view →
UVM	DFS	Quartile	All	0.906	0.529	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RBMS3-AS3–UCS (DFS)

Open the UCS breakdown →