RBMS3-AS3

Across TCGA pan-cancer cohorts, RBMS3-AS3 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of RBMS3-AS3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RBMS3-AS3 RNA is repressed in tumor relative to normal tissue. In most cancer types RBMS3-AS3 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and BLCA are the cancer types where RBMS3-AS3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBMS3-AS3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.724	<.001	11	view →
KICH	Female	All	−1.417	<.001	9	view →
BLCA	Male	IV	−1.772	<.001	8	view →
LUSC	All	III,IV	−1.483	<.001	8	view →
UCEC	All	All	−1.305	<.001	8	view →
THCA	All	All	−0.593	<.001	8	view →
STAD	All	All	−0.832	<.001	7	view →
KIRC	All	II,III,IV	−0.360	<.001	7	view →
LIHC	Male	All	−0.309	<.001	7	view →
BRCA	All	All	−1.372	<.001	6	view →
LUAD	Female	III,IV	−1.154	<.001	6	view →
READ	All	All	−1.086	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

RBMS3-AS3–COAD

Open the COAD breakdown →