RBM7

Across TCGA patient cohorts, RBM7 mutation is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM7-associated genes across cancer lineages are RN7SKP188, PACRG-AS2, and MIR4667. Each is linked with RBM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM7-to-partner and partner-to-RBM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP188 grouped by RBM7-low versus RBM7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM7→partner) and Y-score (partner→RBM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP188 →	+0.158	+6.328	<.001	.001	3	2
SKCM	PACRG-AS2 →	+0.035	+5.970	<.001	.002	3	2
SKCM	MIR4667 →	+0.376	+5.680	<.001	.003	3	1
SKCM	RN7SL560P →	+0.178	+5.097	<.001	.008	3	1
LUSC	RNU7-82P →	+0.514	+7.924	<.001	.008	3	1
UCEC	CRYBB2P1 →	+0.505	+3.021	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

RN7SKP188 by RBM7 expression — SKCM

Explore this box plot interactively →